Vascular free radical release. Ex vivo and in vivo evidence for a flow-dependent endothelial mechanism.
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چکیده
منابع مشابه
Vascular free radical release. Ex vivo and in vivo evidence for a flow-dependent endothelial mechanism.
Mechanisms underlying production of vascular free radicals are unclear. We hypothesized that changes in blood flow might serve as a physiological stimulus for endothelial free radical release. Intact isolated aortas from 45 rabbits were perfused with the spin trap alpha-phenyl-N-tert-butylnitrone (PBN, 20 mmol/L) and formed radical adducts detected by electron paramagnetic resonance spectroscop...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1994
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.74.4.700